' 
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.1
USERS' SCORE
Good
Based on 24 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
5
Total Fat
0.5 g
< 1%**
Vitamin A (from Retinyl Palmitate and Cod Liver Oil)
750 mcg
83%
Vitamin D3 (from Cholecalciferol and Cod Liver Oil)
6.75 mcg (270 IU)
34%
Cod Liver Oil
650 mg
†
Top Medical Research Studies
9
Cod liver oil aids heart health
Cod liver oil supplementation improves cardiovascular and metabolic abnormalities in streptozotocin diabetic rats.
Directly addresses heart disease
We delved into how cod liver oil (CLO) influences heart health, especially in the context of diabetes. Using a study with streptozotocin (STZ)-induced diabetic rats, we treated them with CLO and monitored various cardiovascular metrics over 12 weeks. What we found was quite telling: untreated diabetic rats faced significant increases in blood sugar and harmful lipid levels, while those receiving CLO showed improved weight gain and complete prevention of lipid problems.
Moreover, the study revealed that CLO-treated rats exhibited healthier blood vessel responses and heart function. For instance, we observed that CLO effectively corrected some vasoconstriction issues and improved heart rhythm responses that were otherwise diminished in diabetic rats. The treatment also helped preserve the structural integrity of heart tissue, which often suffers in diabetes.
Overall, this research strongly suggests that cod liver oil can be a valuable supplement for mitigating heart disease risks associated with diabetes. With its rich omega-3 fatty acids and antioxidants, CLO appears to play a protective role in maintaining cardiovascular health in diabetic settings.
Moreover, the study revealed that CLO-treated rats exhibited healthier blood vessel responses and heart function. For instance, we observed that CLO effectively corrected some vasoconstriction issues and improved heart rhythm responses that were otherwise diminished in diabetic rats. The treatment also helped preserve the structural integrity of heart tissue, which often suffers in diabetes.
Overall, this research strongly suggests that cod liver oil can be a valuable supplement for mitigating heart disease risks associated with diabetes. With its rich omega-3 fatty acids and antioxidants, CLO appears to play a protective role in maintaining cardiovascular health in diabetic settings.
Read More
9
Cod liver oil aids heart recovery
[Correction of disorders of cardiac electric stability in post-infarction cardiosclerosis using a diet enriched with polyunsaturated fatty acids].
Direct impact on heart disease
We conducted a study to investigate how cod liver oil, rich in beneficial fatty acids, affects heart health, especially after a heart attack. We fed rats a substance called "eikonole," derived from cod liver oil and enriched with eicosapentaenoic (EPA) and docosahexaenoic (DHA) fatty acids. Following this feeding period, we induced a myocardial infarction and then observed the effects on heart function and electrical stability over the course of 30 days.
Our findings were quite interesting. Eikonole significantly increased the heart's fibrillation threshold by 50%, suggesting it may help the heart resist irregular beats. Furthermore, we noted a threefold decrease in spontaneous extrasystole, which refers to irregular heartbeats, and a reduction of 2.5 times in ectopic activation caused by stimulation of the vagus nerve.
Additionally, we observed that eikonole improved the heart’s functioning during periods of relative physiological rest, although it did not significantly impact blood pressure or the speed of myocardial contraction and relaxation. Overall, our research indicates that cod liver oil could offer protective benefits for heart health after a heart attack, though further studies are needed to understand the full scope of its effects.
Our findings were quite interesting. Eikonole significantly increased the heart's fibrillation threshold by 50%, suggesting it may help the heart resist irregular beats. Furthermore, we noted a threefold decrease in spontaneous extrasystole, which refers to irregular heartbeats, and a reduction of 2.5 times in ectopic activation caused by stimulation of the vagus nerve.
Additionally, we observed that eikonole improved the heart’s functioning during periods of relative physiological rest, although it did not significantly impact blood pressure or the speed of myocardial contraction and relaxation. Overall, our research indicates that cod liver oil could offer protective benefits for heart health after a heart attack, though further studies are needed to understand the full scope of its effects.
Read More
8
Vitamin D improves heart health
The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial.
Study shows vitamin D benefits
We conducted a double-blind, randomized clinical trial to explore how treating vitamin D deficiency affects heart health, specifically in patients with ischemic heart disease (IHD). In our study, we involved 44 patients aged between 40 and 65 who were dealing with low vitamin D levels. They were divided into two groups—one receiving vitamin D supplements and the other a placebo.
Over five weeks, patients in the intervention group received weekly doses of 50,000 units of vitamin D. We measured changes in their lipid profiles, which includes important markers like cholesterol and triglycerides, as well as C-reactive protein (CRP), an indicator of inflammation.
Our findings revealed that vitamin D supplementation led to significant improvements. Patients in the intervention group showed an increase in good cholesterol (HDL) and a decrease in triglycerides, which are both beneficial for heart health. While the placebo group also experienced some minor improvements, the notable changes were primarily in the group receiving vitamin D.
Overall, these results suggest that addressing vitamin D deficiency can have positive effects on lipid levels in IHD patients. This is an encouraging insight for healthcare providers looking to manage heart disease risk more effectively.
Over five weeks, patients in the intervention group received weekly doses of 50,000 units of vitamin D. We measured changes in their lipid profiles, which includes important markers like cholesterol and triglycerides, as well as C-reactive protein (CRP), an indicator of inflammation.
Our findings revealed that vitamin D supplementation led to significant improvements. Patients in the intervention group showed an increase in good cholesterol (HDL) and a decrease in triglycerides, which are both beneficial for heart health. While the placebo group also experienced some minor improvements, the notable changes were primarily in the group receiving vitamin D.
Overall, these results suggest that addressing vitamin D deficiency can have positive effects on lipid levels in IHD patients. This is an encouraging insight for healthcare providers looking to manage heart disease risk more effectively.
Read More
Most Useful Reviews
7
Promotes heart health
Great Cod Liver Oil 650mg is an excellent dosage. It's beneficial for heart disease and general health.
Read More
10
Supports immunity
Cod liver oil significantly benefits skin health and delays ageing. It supports heart health, memory, and reduces diabetes risk. Additionally, it boosts immunity against infections and aids in lowering triglycerides and cholesterol. It’s derived from cod liver, providing higher vitamins A and D than regular fish oils.
Read More
9.5
Combats inflammation
The quality is excellent with clear ingredients, making it one of the best supplements for ageing. I noticed benefits quickly, especially in combating inflammation. The taste is almost non-existent and it supports heart health. The packaging is substantial and it is great for hair health as well.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.1
9
DHA in cod liver oil benefits heart
Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway.
Cod liver oil's impact explored
We explored the effects of docosahexaenoic acid (DHA), a key component of cod liver oil, on heart health, especially after a heart attack. The study investigated whether DHA could play a role in protecting the heart from damage caused by myocardial infarction (MI).
Using both lab-based and animal models, we observed that DHA not only improved the survival of heart cells affected by low oxygen but also reduced overall heart area damage in mice after an MI. Remarkably, we found that DHA enhanced the body's natural process of autophagy, which helps clear out damaged cells and supports heart function.
With the inhibition of autophagy, we noted that the beneficial effects of DHA diminished, underscoring the importance of this process in heart protection. The study showed that DHA works through a specific signaling pathway, the AMPK/mTOR pathway, which is essential for autophagy and improved heart health.
Overall, our findings suggest that incorporating DHA, as found in cod liver oil, could be a promising strategy to support heart health after a heart attack and reduce long-term damage.
Using both lab-based and animal models, we observed that DHA not only improved the survival of heart cells affected by low oxygen but also reduced overall heart area damage in mice after an MI. Remarkably, we found that DHA enhanced the body's natural process of autophagy, which helps clear out damaged cells and supports heart function.
With the inhibition of autophagy, we noted that the beneficial effects of DHA diminished, underscoring the importance of this process in heart protection. The study showed that DHA works through a specific signaling pathway, the AMPK/mTOR pathway, which is essential for autophagy and improved heart health.
Overall, our findings suggest that incorporating DHA, as found in cod liver oil, could be a promising strategy to support heart health after a heart attack and reduce long-term damage.
Read More
9
Cod liver oil aids heart health
Cod liver oil supplementation improves cardiovascular and metabolic abnormalities in streptozotocin diabetic rats.
Directly addresses heart disease
We delved into how cod liver oil (CLO) influences heart health, especially in the context of diabetes. Using a study with streptozotocin (STZ)-induced diabetic rats, we treated them with CLO and monitored various cardiovascular metrics over 12 weeks. What we found was quite telling: untreated diabetic rats faced significant increases in blood sugar and harmful lipid levels, while those receiving CLO showed improved weight gain and complete prevention of lipid problems.
Moreover, the study revealed that CLO-treated rats exhibited healthier blood vessel responses and heart function. For instance, we observed that CLO effectively corrected some vasoconstriction issues and improved heart rhythm responses that were otherwise diminished in diabetic rats. The treatment also helped preserve the structural integrity of heart tissue, which often suffers in diabetes.
Overall, this research strongly suggests that cod liver oil can be a valuable supplement for mitigating heart disease risks associated with diabetes. With its rich omega-3 fatty acids and antioxidants, CLO appears to play a protective role in maintaining cardiovascular health in diabetic settings.
Moreover, the study revealed that CLO-treated rats exhibited healthier blood vessel responses and heart function. For instance, we observed that CLO effectively corrected some vasoconstriction issues and improved heart rhythm responses that were otherwise diminished in diabetic rats. The treatment also helped preserve the structural integrity of heart tissue, which often suffers in diabetes.
Overall, this research strongly suggests that cod liver oil can be a valuable supplement for mitigating heart disease risks associated with diabetes. With its rich omega-3 fatty acids and antioxidants, CLO appears to play a protective role in maintaining cardiovascular health in diabetic settings.
Read More
9
Cod liver oil aids heart recovery
[Correction of disorders of cardiac electric stability in post-infarction cardiosclerosis using a diet enriched with polyunsaturated fatty acids].
Direct impact on heart disease
We conducted a study to investigate how cod liver oil, rich in beneficial fatty acids, affects heart health, especially after a heart attack. We fed rats a substance called "eikonole," derived from cod liver oil and enriched with eicosapentaenoic (EPA) and docosahexaenoic (DHA) fatty acids. Following this feeding period, we induced a myocardial infarction and then observed the effects on heart function and electrical stability over the course of 30 days.
Our findings were quite interesting. Eikonole significantly increased the heart's fibrillation threshold by 50%, suggesting it may help the heart resist irregular beats. Furthermore, we noted a threefold decrease in spontaneous extrasystole, which refers to irregular heartbeats, and a reduction of 2.5 times in ectopic activation caused by stimulation of the vagus nerve.
Additionally, we observed that eikonole improved the heart’s functioning during periods of relative physiological rest, although it did not significantly impact blood pressure or the speed of myocardial contraction and relaxation. Overall, our research indicates that cod liver oil could offer protective benefits for heart health after a heart attack, though further studies are needed to understand the full scope of its effects.
Our findings were quite interesting. Eikonole significantly increased the heart's fibrillation threshold by 50%, suggesting it may help the heart resist irregular beats. Furthermore, we noted a threefold decrease in spontaneous extrasystole, which refers to irregular heartbeats, and a reduction of 2.5 times in ectopic activation caused by stimulation of the vagus nerve.
Additionally, we observed that eikonole improved the heart’s functioning during periods of relative physiological rest, although it did not significantly impact blood pressure or the speed of myocardial contraction and relaxation. Overall, our research indicates that cod liver oil could offer protective benefits for heart health after a heart attack, though further studies are needed to understand the full scope of its effects.
Read More
9
Cod liver oil benefits heart health
Effects of n-3 polyunsaturated fatty acids on coronary heart disease.
Significant study on cod liver oil
We explored the effects of cod liver oil on coronary heart disease (CHD) by evaluating how its fatty acids, particularly the balance of n-6 and n-3 polyunsaturated fatty acids, influence heart health. In our analysis, we found that individuals who consumed cod liver oil exhibited a significant reduction in arachidonic acid levels in their heart cells, which is generally linked to better heart health.
Our research indicated that dietary fish oil could minimize the levels of arachidonic acid, a fatty acid connected to increased risk of cardiovascular issues, while promoting the presence of docosahexaenoic acid (DHA), which is beneficial for heart muscle. The results highlighted that a lower ratio of arachidonic acid to DHA in heart tissues was associated with reduced incidence of sudden cardiac events and ventricular fibrillation in experiments with rats.
Therefore, incorporating cod liver oil into our diets may potentially offer valuable benefits in protecting against heart disease. Interestingly, the relationship between these fatty acids and heart health suggests that fostering a balance between n-6 and n-3 fatty acids is crucial for enhancing our resilience to stress and promoting heart health as we age.
Our research indicated that dietary fish oil could minimize the levels of arachidonic acid, a fatty acid connected to increased risk of cardiovascular issues, while promoting the presence of docosahexaenoic acid (DHA), which is beneficial for heart muscle. The results highlighted that a lower ratio of arachidonic acid to DHA in heart tissues was associated with reduced incidence of sudden cardiac events and ventricular fibrillation in experiments with rats.
Therefore, incorporating cod liver oil into our diets may potentially offer valuable benefits in protecting against heart disease. Interestingly, the relationship between these fatty acids and heart health suggests that fostering a balance between n-6 and n-3 fatty acids is crucial for enhancing our resilience to stress and promoting heart health as we age.
Read More
8
Vitamin D improves heart health
The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial.
Study shows vitamin D benefits
We conducted a double-blind, randomized clinical trial to explore how treating vitamin D deficiency affects heart health, specifically in patients with ischemic heart disease (IHD). In our study, we involved 44 patients aged between 40 and 65 who were dealing with low vitamin D levels. They were divided into two groups—one receiving vitamin D supplements and the other a placebo.
Over five weeks, patients in the intervention group received weekly doses of 50,000 units of vitamin D. We measured changes in their lipid profiles, which includes important markers like cholesterol and triglycerides, as well as C-reactive protein (CRP), an indicator of inflammation.
Our findings revealed that vitamin D supplementation led to significant improvements. Patients in the intervention group showed an increase in good cholesterol (HDL) and a decrease in triglycerides, which are both beneficial for heart health. While the placebo group also experienced some minor improvements, the notable changes were primarily in the group receiving vitamin D.
Overall, these results suggest that addressing vitamin D deficiency can have positive effects on lipid levels in IHD patients. This is an encouraging insight for healthcare providers looking to manage heart disease risk more effectively.
Over five weeks, patients in the intervention group received weekly doses of 50,000 units of vitamin D. We measured changes in their lipid profiles, which includes important markers like cholesterol and triglycerides, as well as C-reactive protein (CRP), an indicator of inflammation.
Our findings revealed that vitamin D supplementation led to significant improvements. Patients in the intervention group showed an increase in good cholesterol (HDL) and a decrease in triglycerides, which are both beneficial for heart health. While the placebo group also experienced some minor improvements, the notable changes were primarily in the group receiving vitamin D.
Overall, these results suggest that addressing vitamin D deficiency can have positive effects on lipid levels in IHD patients. This is an encouraging insight for healthcare providers looking to manage heart disease risk more effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 24 Reviews
8.5
10
Supports immunity
Cod liver oil significantly benefits skin health and delays ageing. It supports heart health, memory, and reduces diabetes risk. Additionally, it boosts immunity against infections and aids in lowering triglycerides and cholesterol. It’s derived from cod liver, providing higher vitamins A and D than regular fish oils.
Read More
9.5
Combats inflammation
The quality is excellent with clear ingredients, making it one of the best supplements for ageing. I noticed benefits quickly, especially in combating inflammation. The taste is almost non-existent and it supports heart health. The packaging is substantial and it is great for hair health as well.
Read More
9.5
Lowers bad cholesterol
This product is fantastic; it's known to lower bad cholesterol, making it highly recommended for heart disease. A relative reported improved blood sugar levels as well.
8.8
Reduces inflammation
I recommend fish oil for my sister's joint issues. May God heal her; she feels better and her pain eases. The ingredients are crucial for inflammation reduction, heart health, and cholesterol management. The quality is excellent, and the packaging lasts a long time. She consistently repurchases it due to the noticeable difference.
Read More
8.8
Rich in omega
This product is wonderful, with a pleasant dosage. Though it may have a fishy smell after a while, it’s fortified with vitamin A and rich omega. It’s beneficial for heart and blood vessel health, and has anti-inflammatory properties. The packaging is economical and I recommend it.
